Tretizen 10 (Zenlabs)

Tretizen-10 is manufactured by Zen Labs and contains the active substance Isotretinoin, which is a retinoid and vitamin A derivative.

Isotretinoin is used to treat severe cases of acne that does not get better with other treatments or antibiotics.

The drug is also used to treat rosacea, perioral dermatitis, seborrheic dermatitis, folliculitis, granuloma annulus, sarcoidosis, various keratinization disorders, and photo-aging.

Effects of Isotretinoin

Isotretinoin has many effects, which include:

• Anti-seborrheic
• Anti-inflammatory
• Sebostatic
• Immunomodulatory and kerato-modulatory

Isotretinoin enhances the skin’s regeneration processes and it has the ability to influence the composition of sebum, reduce its production, and ensure rapid excretion from the sebaceous glands. When the drug is used, the production of the sebaceous glands is suppressed, narrowing of the ducts, and a reduction in their number.

Isotretinoin’s half-life is 19 hours.

Side effects of the drug

Side effects from the use of Isotretinoin include:

• Severe dryness of the skin.
• Sore lips.
• Itching and flaking of the skin on the hands and feet.
• Irritation on the skin and mucous membranes.
• Impaired liver function.

Dry skin may be caused due to exposure to sunlight so while using the drug, we recommend that you do not sunbathe during this time and also use sunscreen when you are outside in the sun.

Using Isotretinoin

We recommend the use of the drug together with a meal.

For cases of severe acne, the dosage should be determined individually, but it is normally used at a dosage of 0.4 – 0.5 mg / 2lbs of body weight per day.

For mild to moderate forms of acne, we recommend a dosage of 10 – 20mg per day.

The length of use is dependent on the dosage being used so it is different for each individual.